| Date | Size | Title | Author |
| January 4, 2015 | 21 x 21 | The Descent of Man | Finn Vigeland |
| January 11, 2015 | 21 x 21 | Personal Statements | Peter A. Collins |
| January 18, 2015 | 21 x 21 | Changelings | Joe Krozel |
| January 25, 2015 | 21 x 21 | Twist Ending | Alan Arbesfeld |
| February 1, 2015 | 21 x 21 | This N' That | David Steinberg |
| February 8, 2015 | 21 x 21 | Multifaceted | Jeremy Newton |
| February 15, 2015 | 21 x 21 | Split Ends | Ellen Leuschner and Jeff Chen |
| February 22, 2015 | 21 x 21 | Flip-Flops | Patrick Berry |
| March 1, 2015 | 21 x 21 | Noted Anniversary | Finn Vigeland |
| March 8, 2015 | 21 x 21 | 3.1415926 ... | Tom McCoy |
| March 15, 2015 | 21 x 21 | Making Connections | Dan Feyer |
| March 22, 2015 | 21 x 21 | Upsides | Jeremy Newton |
| March 29, 2015 | 21 x 21 | California, Here I Come | Alan Arbesfeld |
| April 5, 2015 | 21 x 21 | The Captain Goes Down with the Ship | Tom McCoy |
| April 12, 2015 | 21 x 21 | Look What Turned Up! | Jeff Chen |
| April 19, 2015 | 21 x 21 | Double Down | Don Gagliardo and Zhouqin Burnikel |
| April 26, 2015 | 21 x 21 | Which is Wish | Patrick Berry |
| May 3, 2015 | 21 x 21 | Non-Starters | Dan Schoenholz |
| May 10, 2015 | 21 x 21 | Literary Circles | Jacob Stulberg |
| May 17, 2015 | 21 x 21 | To-Do List (Abridged) | Joe Krozel |
| May 24, 2015 | 23 x 23 | A Tale of Many Cities | Kevin G. Der |
| May 31, 2015 | 21 x 21 | Making Projections | Tom McCoy |
| June 7, 2015 | 21 x 21 | The Call of the Race | Samuel A. Donaldson |
| June 14, 2015 | 21 x 21 | The in Crowd | Randolph Ross |
| June 21, 2015 | 21 x 21 | Climbing the Corporate Ladder | Timothy Polin |
| June 28, 2015 | 21 x 21 | Getting in the Final Word | Jeremy Newton |
| July 5, 2015 | 21 x 21 | Heads of State | Elizabeth C. Gorski |
| July 12, 2015 | 21 x 21 | Start Again | Patrick Berry |
| July 19, 2015 | 21 x 21 | The Short Form | Tom McCoy |
| July 26, 2015 | 21 x 21 | No Escape | Ellen Leuschner and Jeff Chen |
| August 2, 2015 | 21 x 21 | Literally Speaking | Matt Ginsberg |
| August 9, 2015 | 21 x 21 | Help Wanted | Melanie Miller |
| August 16, 2015 | 21 x 21 | As It Were | Don Gagliardo and Zhouqin Burnikel |
| August 23, 2015 | 21 x 21 | Musical Remixes | Joel Fagliano |
| August 30, 2015 | 21 x 21 | Conflicting Advice | Lee Taylor |
| September 6, 2015 | 21 x 21 | Double Digits | Patrick Berry |
| September 13, 2015 | 21 x 21 | To Put It Differently | Joe DiPietro |
| September 20, 2015 | 21 x 21 | Put a Lid on It! | Jason Mueller and Jeff Chen |
| September 27, 2015 | 21 x 21 | Mark My Words | Tom McCoy |
| October 4, 2015 | 21 x 21 | Sound Argument | Jeremy Newton |
| October 11, 2015 | 21 x 21 | For Variety's Sake | David J. Kahn |
| October 18, 2015 | 21 x 21 | Big Names in E-Tail | Dan Schoenholz |
| October 25, 2015 | 21 x 21 | Halloween Costumes | Bill Zais |
| November 1, 2015 | 21 x 21 | Frame Job | Zhouqin Burnikel |
| November 8, 2015 | 21 x 21 | Three-Peat | Tracy Gray |
| November 15, 2015 | 21 x 21 | Having Aspirations | Alan Arbesfeld |
| November 22, 2015 | 21 x 21 | Right On, Right On! | Samuel A. Donaldson and Jeff Chen |
| November 29, 2015 | 21 x 21 | Four-Letter Words | Alex Vratsanos |
| December 6, 2015 | 21 x 21 | With Drawl | Patrick Berry |
| December 13, 2015 | 21 x 21 | Bands Together | Tracy Gray and Andrea Carla Michaels |
| December 20, 2015 | 21 x 21 | Rebranding | Peter Wentz |
| December 27, 2015 | 21 x 21 | Binary Code | Don Gagliardo and Zhouqin Burnikel |