| Date | Size | Title | Author |
| January 4, 2004 | 21 x 21 | Alternate Job Titles | Patrick Merrell |
| January 11, 2004 | 21 x 21 | The Long and the Short of It | Alan Arbesfeld |
| January 18, 2004 | 21 x 21 | Good News/Bad News | Arlan and Linda Bushman |
| January 25, 2004 | 21 x 21 | Chicken Little | Harvey Estes and Nancy Salomon |
| February 1, 2004 | 23 x 23 | Film Sounds | Roy Leban |
| February 8, 2004 | 21 x 21 | Overheard at the Poker Game | Randolph Ross |
| February 15, 2004 | 21 x 21 | Names, Names, Names | Derrick Niederman |
| February 22, 2004 | 21 x 21 | Riddle-Dee-Dee | Nancy Nicholson Joline |
| February 29, 2004 | 21 x 21 | Leap Day | Patrick Merrell |
| March 7, 2004 | 21 x 21 | "That's Disgusting" | Tyler Hinman |
| March 14, 2004 | 23 x 23 | Moonlighting | Craig Kasper |
| March 21, 2004 | 21 x 21 | Movie Sequels That Were Never Made | Roy Leban |
| March 28, 2004 | 21 x 21 | What's the Meaning of This? | David J. Kahn |
| April 4, 2004 | 21 x 21 | It Takes All Kinds | Manny Nosowsky |
| April 11, 2004 | 21 x 21 | We're #2! | Patrick Merrell |
| April 18, 2004 | 21 x 21 | Canonized | Richard Chisholm |
| April 25, 2004 | 23 x 23 | V Formation | Elizabeth C. Gorski |
| May 2, 2004 | 21 x 21 | Self-Defining | Derrick Niederman |
| May 9, 2004 | 21 x 21 | Moving the Bar | Charles M. Deber |
| May 16, 2004 | 21 x 21 | The Echo Effect | Patrick Berry |
| May 23, 2004 | 21 x 21 | Grooming for Hollywood | Deb Amlen and Nancy Salomon |
| May 30, 2004 | 21 x 21 | Critiquing the Critics | Brendan Emmett Quigley |
| June 6, 2004 | 21 x 21 | The Sunday Funnies | Patrick Merrell |
| June 13, 2004 | 21 x 21 | Roget and Me | Richard Silvestri |
| June 20, 2004 | 21 x 21 | Pack of 20 | Manny Nosowsky |
| June 27, 2004 | 21 x 21 | Hear! Hear! | Peter Abide and Steven Kahn |
| July 4, 2004 | 23 x 23 | Banner Day | Elizabeth C. Gorski |
| July 11, 2004 | 21 x 21 | You See Now? | Randolph Ross |
| July 18, 2004 | 21 x 21 | Ambiguous Job Recommendations | Seth A. Abel |
| July 25, 2004 | 21 x 21 | Cued In | Brendan Emmett Quigley |
| August 1, 2004 | 21 x 21 | Political Combat | Randolph Ross |
| August 8, 2004 | 21 x 21 | Tap, Tap, Tap | Bill Zais |
| August 15, 2004 | 23 x 23 | Catch Phrase | Brendan Emmett Quigley |
| August 22, 2004 | 21 x 21 | That's Funnery | Cathy Millhauser |
| August 29, 2004 | 21 x 21 | Where It's At | Manny Nosowsky |
| September 5, 2004 | 21 x 21 | At the Company Picnic | Patrick Merrell |
| September 12, 2004 | 21 x 21 | Furnishing Touches | Patrick Berry |
| September 19, 2004 | 21 x 21 | I.E., Not I | Kyle Mahowald |
| September 26, 2004 | 21 x 21 | Overheard in Underground New York | Joe DiPietro |
| October 3, 2004 | 21 x 21 | Abridged Versions | Randolph Ross |
| October 10, 2004 | 21 x 21 | Love Connection | Elizabeth C. Gorski |
| October 17, 2004 | 21 x 21 | You Will be Missed | Manny Nosowsky |
| October 24, 2004 | 21 x 21 | The Referee of Romance | Patrick Berry |
| October 31, 2004 | 21 x 21 | Gridiron Glossary | Patrick Merrell |
| November 7, 2004 | 21 x 21 | No More Aches | Con Pederson |
| November 14, 2004 | 21 x 21 | Blue Streak | Harvey Estes and Nancy Salomon |
| November 21, 2004 | 21 x 21 | "National" Holiday | Kumar Balani |
| November 28, 2004 | 21 x 21 | Florida Key | Elizabeth C. Gorski |
| December 5, 2004 | 21 x 21 | From the Presidential Record Books | David J. Kahn |
| December 12, 2004 | 21 x 21 | Years on End | Lee Glickstein and Nancy Salomon |
| December 19, 2004 | 21 x 21 | At the Present Time | Frances Hansen (1919-2004) |
| December 26, 2004 | 21 x 21 | The Other Half | Hal Turner |